| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Theophylline
MessagePerformed in Chemistry
Performed at SQL for BCGMC, Page, BCCH, WMC, BPMC, TCH, BBMC, OCH, PCMH, EMCH, SRMC, WyMC, MMC, BFCMC, NCMC.
Performed at SQL for BCGMC, Page, BCCH, WMC, BPMC, TCH, BBMC, OCH, PCMH, EMCH, SRMC, WyMC, MMC, BFCMC, NCMC.
Test Code
THEO
CPT Codes
80198
Preferred Specimen
Green LiHep, Plasma for facilities performing on site.
Other Acceptable Specimens
Red top, serum
Instructions
For facilities sending to Sonora Quest Laboratories, see link below for specimen details, methodology, setup schedule and reference ranges.
Specimen Stability
Refrigerated - 7 days
Frozen - 60 days
Frozen - 60 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Collected in an outdated/expired tube
Hemolyzed, icteric or lipemic
Contaminated
Hemolyzed, icteric or lipemic
Contaminated
FDA Status
FDA Approved
Setup Schedule
Daily, Sunday through Saturday
Report Available
Less than 4 hours
Clinical Significance
Theophylline (1,3-dimethylxanthine), a bronchodilator, is widely used to treat patients with asthma, apnea (temporary asphyxia), and other obstructive lung diseases. Monitoring of theophylline concentrations in serum is essential, since indicviduals can vary in their rates of theophylline clearance 1,2 and severe toxicity has been observed without prior occurrence of minor side effects. 3 Moreover, several factors can alter theophylline elimination. Theophylline elimination is slowed in obese patients, patients with hepatic disease, and in those on a high carbohydrate, low protein diet. Premature infants have very low rates of theophylline elimination. 4 Conversely, theophylline elimination is more rapid among cigarette smokers. 5 In combination with other clinical data, monitoring serum theophylline levels may provide the physician with useful information to aid in adjusting patient dosage to achieve optmal therapeutic effect while avoiding drug toxicity.
Additional Information
Theophylline
