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Tacrolimus, Highly Sensitive, LC/MS/MS
MessageLab only orderable at all sites except BLMC.
Test Code
FK506-HS
Quest Code
70007
Alias/See Also
#FK506-HS
CPT Codes
80197 <br><strong>This test is not available for New York patient testing. For New York patient testing use test code 13609.</strong>
Preferred Specimen
2 mL whole blood collected in an EDTA (lavender-top) tube
Patient Preparation
Collect specimen 1 hour prior to next dose (12 hour trough)
Minimum Volume
1 mL
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 7 days
Refrigerated: 7 days
Frozen: 60 days
Refrigerated: 7 days
Frozen: 60 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Clotted specimen
Methodology
Chromatography/Mass Spectrometry
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Set up: Mon-Sat; Report Available: 2-4 days
Reference Range
No definitive therapeutic or toxic ranges have been established. Optimal blood drug levels are influenced by type of transplant, patient response, time post-transplant, co-administration of other drugs, and drug formulation.
The following trough range is a suggested guideline: 5.0-20.0 mcg/L
The following trough range is a suggested guideline: 5.0-20.0 mcg/L
Clinical Significance
Tacrolimus is an immunosuppressant drug which has been shown to be effective for the treatment of rejection following transplantation.
Performing Laboratory
MedFusion
2501 South State Highway 121 Suite 1100
Lewisville, TX 75067-8188