Derm. pteronyssinus (D1) IgE (2721X)

Test Code

Quest Code

Alias/See Also
House Dust Mites

CPT Codes

Preferred Specimen
0.3 mL serum

Minimum Volume
0.15 mL

Transport Container
Serum separator tube (SST)

Transport Temperature

Specimen Stability
Room temperature: 14 days
Refrigerated: 14 days
Frozen: 30 days

Immunoassay (IA)

Setup Schedule
A.M. Sets up 6 days a week.

Reference Range
See Laboratory Report

Clinical Significance

This allergen-specific IgE antibody test quantifies an individual's IgE response to Dermatophagoides pteronyssinus, a species of house dust mites that can cause atopic reactivity and allergic disease affecting the eyes, airways, skin, and occasionally the circulation [1]. This test is an in vitro quantitative assay that is intended to be used in conjunction with other clinical information to aid in the diagnosis of allergic diseases [2].

While allergen-specific serum IgE testing is considered comparable to skin testing in many instances, both the American Academy of Allergy, Asthma, and Immunology and the American College of Allergy, Asthma, and Immunology recognize that allergen-specific serum IgE testing may be preferred in some clinical situations. These include (1) the presence of widespread skin disease, (2) the recent use of antihistamines or other medications that can affect the results of allergy skin tests, (3) uncooperative patients, and (4) medical history suggesting that allergen skin testing would pose a significant risk for a serious allergic reaction [2].

A definitive clinical diagnosis of allergy should not be based on the results of any single diagnostic method but should be made by a trained healthcare provider after all clinical and laboratory findings have been evaluated.

More specific information about this allergen can be found on the following web page:

1. Miller JD. Clin Rev Allergy Immunol. 2019;57(3):312-329.
2. Bernstein IL, et al. Ann Allergy Asthma Immunol. 2008;100(3 Suppl 3)S1-S148.

Performing Laboratory
Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano, CA 92690-6130

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.