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Rickettsia (RMSF) Antibodies (IgG, IgM) with Reflex to Titers
Test CodeROCKYM
Quest Code
6419
Alias/See Also
6419
CPT Codes
86757 (x2)
Includes
If RMSF IgG is Detected, then RMSF IgG Titer will be performed at an additional charge (CPT code(s): 86757).
If RMSF IgM is Detected, then RMSF IgM Titer will be performed at an additional charge (CPT code(s): 86757).
If RMSF IgM is Detected, then RMSF IgM Titer will be performed at an additional charge (CPT code(s): 86757).
Preferred Specimen
1 mL serum
Minimum Volume
0.2 mL
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days
Refrigerated: 14 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly lipemic
Methodology
Immunofluorescence Assay (IFA)
Setup Schedule
Set up: Tue-Sat; Report available: 1-4 days
Report Available
Maximum Laboratory Turn Around Time 6 days.
Limitations
Even after infection has been treated, positive results may persist. False-positive reactions may occur during pregnancy.
Reference Range
Screen | Titer | |||
RMSF (IgG) | Not detected | <1:64 | ||
RMSF (IgM) | Not detected | <1:64 |
Clinical Significance
Antigen specific IgG and IgM titers allow rapid diagnosis of infection by any of the spotted fever group of rickettsial agents. This group of agents include R. rickettsii (Rocky Mountain Spotted Fever) and R. akari (rickettsial pox), both seen in the continental United States.
Performing Laboratory
Quest Diagnostics Nichols Institute |
33608 Ortega Highway |
San Juan Capistrano, CA 92675-2042 |