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Infectious Mononucleosis Screen
MessageThe Mono Screen detects heterophilic antibodies that develop during the acute phase of infectious mononucleosis.
Test Code
Mono-TEST
Alias/See Also
Infectious Mononucleosis Screen
Preferred Specimen
Whole Blood ONLY (EDTA or heparin as the anticoagulant)
Minimum Volume
1mL
Specimen Stability
Room Temperature/ Ambient: 24 hours
Refrigerated: 24 hours
Frozen: Not acceptable
Refrigerated: 24 hours
Frozen: Not acceptable
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Serum/ Plasma
Refrigerated specimens
Frozen specimens
Refrigerated specimens
Frozen specimens
Methodology
Immunochromatographic dipstick
Setup Schedule
Setup daily
Report Available
Same day
Clinical Significance
The Mononucleosis Screen measures heterophilic antibodies associated with infectious mononucleosis. Infectious mononucleosis is typically due to the Epstein-Barr virus (EBV). In patients with infectious mononucleosis, a positive result may be present as early as the fourth day of illness, and by the twenty-first day of illness, 90% of patients will exhibit a positive test. Heterophilic antibodies detected by the mononucleosis screen can be caused by conditions other than infectious mononucleosis. Therefore a positive result may indicate that a person has a typical case of infectious mononucleosis, but does not confirm the presence of EBV infection.
Performing Laboratory
Performed on site.
