Extended Myositis Panel

Message

Requires Med. Dir approval

Test Code

MYOSPNL-ARUP

Alias/See Also

ARUP Test code 3001781
MYOS EXT

CPT Codes
83516 x8; 86235 x6; 84182 x4

Includes

SSA-52 (Ro52) (ENA) Antibody, IgG

Jo-1 (Histidyl-tRNA Synthetase) Ab, IgG

PM/Scl 100 Antibody, IgG

Mi-2 (nuclear helicase protein) Antibody

PL-7 (threonyl-tRNA synthetase) Antibody

PL-12 (alanyl-tRNA synthetase) Antibody

P155/140 Antibody

EJ (glycyl-tRNA synthetase) Antibody

Ku Antibody

SRP (Signal Recognition Particle) Ab

OJ (isoleucyl-tRNA synthetase) Antibody

SSA-60 (Ro60) (ENA) Antibody, IgG

Fibrillarin (U3 RNP) Ab, IgG

Myositis Panel Interpretive Data

SAE1 (SUMO activating enzyme) Ab

MDA5 (CADM-140) Ab

NXP2 (Nuclear matrix protein-2) Ab

TIF-1 gamma (155 kDa) Ab

Preferred Specimen

Collect 2 full SST's
Separate from cells ASAP or within 2 hours of collection. Transfer three 1 mL serum aliquots to ARUP Standard Transport Tubes.

Instructions

See link below for specimen details, methodology, setup schedule and reference ranges.

Transport Temperature

Refrigerated

Specimen Stability

Ambient: 48 hours
Refrigerated: 2 weeks
Frozen: 1 year

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Hemolyzed, hyperlipemic, icteric, heat-treated or contaminated specimens.

Methodology
Qualitative Immunoprecipitation/Semi-Quantitative Multiplex Bead Assay/Qualitative Immunoblot

FDA Status
LDT: This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.

Setup Schedule

Sunday-Saturday

Report Available

7-18 days from receipt at ARUP Lab

Clinical Significance

May be useful for differential evaluation of polymyositis, dermatomyositis, necrotizing autoimmune myopathy, or overlap syndromes associated with connective tissue disease.

Performing Laboratory
ARUP Laboratories
500 Chipeta Way
Salt Lake City, UT 84108

Additional Information
Extended Myositis Panel

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.