Drug Monitoring, Barbiturates, Quantitative, Urine

Test Code

CONFBARBR/U

Quest Code

39387

CPT Codes
80345 (HCPCS: G0480)

Includes

If you require medMATCH for this order code, you must also order code 39158 - Prescribed Drugs, medMATCH®. If 39158 is ordered, all Drug Monitoring order codes will be treated as medMATCH.

If this test code is not ordered with 39158, all medMATCH result codes will be DNR’d.
.
Amobarbital, Butalbital, Pentobarbital, Secobarbital, Phenobarbital

Preferred Specimen

9 mL urine in a clinical drug test transport vial

Minimum Volume

5 mL

Other Acceptable Specimens

Urine collected in urine collection container

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 14 days
Refrigerated: 14 days
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Preserved samples

Methodology
Mass Spectrometry (MS)

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

Set up: Mon-Sat; Report available: 2-3 days

Reference Range

Amobarbital	<100 ng/mL
Butalbital	<100 ng/mL
Pentobarbital	<100 ng/mL
Secobarbital	<100 ng/mL
Phenobarbital	<100 ng/mL

Clinical Significance

The barbiturate class of drugs are substances that are traditionally classified as sedatives. Their principle uses are to calm the patient, produce drowsiness, and/or promote sleep. They are central nervous system (CNS) depressants. The test is a definitive assay using gas chromatography mass spectroscopy (GC/MS) methodology. Therapeutic urine drug monitoring of the barbiturates is important for ensuring compliance to treatment strategies, as well as ensuring non-diversion for illicit purposes. Urine or oral fluid are the specimens of choice for routine monitoring of patients taking prescription drugs. Use of serum/plasma should be limited to anuretic patients, or where a patient's clinical appearance does not coincide with their prescribed medications. No single monitoring approach provides adequate information about the pattern or dose of patient drug use. Safest prescribing habits should include a combination of tools and laboratory test results to correctly detect drug use patterns. Quantitative values cannot be used to assess the drug dose, because the drug is extensively metabolized and excreted in the urine. Quantitative values cannot be used to assess the drug dose, because the drug is extensively metabolized and excreted in the urine.

Performing Laboratory
Quest Diagnostics Valencia Nichols Institute
27027 Tourney Road
Valencia, CA 91355-5386

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.