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DIC Panel
MessagePerformed in Coagulation and Hematology
Test Code
DIC
Includes
PT
INR
APTT
FIB
DDIQ
PLTCT
IPF
SCHISTOCYTES
INR
APTT
FIB
DDIQ
PLTCT
IPF
SCHISTOCYTES
Preferred Specimen
Lt Blue Top
Lavendar Top
Lavendar Top
Minimum Volume
2.7 mL Na Cit
2.0 mL EDTA
2.0 mL EDTA
Instructions
The light blue capped tubes, containing 3.2% buffered sodium citrate, used for coagulation testing must be allowed to fill completely (after filling a small air space will normally be present). We cannot accept a short filled tube.
For patients having a hematocrit greater than 55%, contact the hospital coagulation department to obtain a special collection tube.
Do not spin or separate plasma from the purple top tube.
Light Blue Top and Lavendar Top tubes should be obtained from the same collection time.
For patients having a hematocrit greater than 55%, contact the hospital coagulation department to obtain a special collection tube.
Do not spin or separate plasma from the purple top tube.
Light Blue Top and Lavendar Top tubes should be obtained from the same collection time.
Clinical Significance
Disseminated intravascular coagulation (DIC) involves abnormal, excessive generation of thrombin and fibrin in the circulating blood. During the process, increased platelet aggregation and coagulation factor consumption occur. DIC that evolves slowly (over weeks or months) causes primarily venous thrombotic and embolic manifestations; DIC that evolves rapidly (over hours or days) causes primarily bleeding. Severe, rapidly evolving DIC is diagnosed by demonstrating thrombocytopenia, an elevated partial thromboplastin time and prothrombin time, increased levels of plasma D-dimers (or serum fibrin degradation products), and a decreasing plasma fibrinogen level.