Amiodarone

Test Code

AMIODAR

Quest Code

36721

CPT Codes
80151

Includes

Amiodarone and Desethylamiodarone

Preferred Specimen

3 mL serum collected in a red-top tube (no gel)

Minimum Volume

1 mL

Other Acceptable Specimens

Plasma collected in: EDTA (lavender-top) tube, sodium heparin (green-top) tube, or lithium heparin (green-top) tube

Instructions

Centrifuge and immediately separate serum or plasma specimens from the cells into a clean, plastic, screw-cap vial. Do not use gel barrier/Serum Separator Tube (SST^®).

Transport Temperature

Frozen

Specimen Stability

Room temperature: 48 hours
Refrigerated: 4 days
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Hemolysis • Lipemia • Gel barrier/serum separator tube (SST)

Methodology
Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

Sets up 3 days a week.

Reference Range

Amiodarone	1.5-2.5 mcg/mL
Desethylamiodarone	1.5-2.5 mcg/mL
Toxic	>2.5 mcg/mL

Toxic effects have been observed at levels as low as 2.0 mcg/mL.

Clinical Significance

Amiodarone is an antiarrythmic drug. Therapeutic drug monitoring is useful to monitor compliance and avoid toxicity.

Performing Laboratory
Quest Diagnostics Valencia Nichols Institute
27027 Tourney Road
Valencia, CA 91355-5386

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.