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Copeptin
Test CodeCOPEPTIN
Quest Code
37740
Alias/See Also
Arginine Vasopressin
AVP
C-Terminal pro-vasopressin,CT-proAVP
ADH
AVP
C-Terminal pro-vasopressin,CT-proAVP
ADH
CPT Codes
86255
Preferred Specimen
1 mL serum
Minimum Volume
0.5 mL
Other Acceptable Specimens
Plasma collected in: EDTA (lavender-top) tube or sodium heparin (green-top) tube
Transport Temperature
Frozen
Specimen Stability
Room temperature: 24 hours
Refrigerated: 72 hours
Frozen: 28 days
Refrigerated: 72 hours
Frozen: 28 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis
Methodology
Immunofluorescence Assay (IFA)
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Night Sets up 3 days a week.
Report Available
Reports in 3 to 5 days.
Reference Range
0-2 Years | Not Established |
3-17 Years | 2.4-26.0 pmol/L |
≥18 Years | ≤13.7 pmol/L |
Clinical Significance
The Copeptin test is used in the diagnosis of central diabetes insipidus and in the differential diagnosis of central or nephrogenic diabetes insipidus. It is a reliable surrogate marker for arginine vasopressin (AVP).
Performing Laboratory
Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano, CA 92675-2042