Methylmalonic Acid, Urine with Creatinine

Message
Non-Interface to QNI, place order in Quanum


Test Code
MTACU


Quest Code
91032


Alias/See Also
91032


CPT Codes
82570, 83921

Preferred Specimen
1.7 mL urine - no preservative in a sterile screw cap container


Minimum Volume
0.6 mL


Other Acceptable Specimens
In a sterile, screw-cap container (no preservative): 24-hour urine • Random clean-catch urine • Catheterized urine • First void clean-catch


Instructions
Do not use preservatives


Transport Temperature
Refrigerated (cold packs)


Specimen Stability
Room temperature: 4 days
Refrigerated: 12 days
Frozen -20°: 30 days
Frozen -70°: 90 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Received room temperature • Acidified urine


Methodology
Chromatography/Mass Spectrometry

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule
P.M. Sets up 2 days a week.


Reference Range
Methylmalonic Acid, Urine0.3-2.2 mmol/mol creat

Creatinine, Random Urine
0-6 Months0.18-2.48 mmol/L
7-11 Months0.18-2.74 mmol/L
1-2 Years0.18-9.72 mmol/L
3-8 Years0.18-11.49 mmol/L
9-12 Years0.18-14.14 mmol/L
>12 Years1.77-23.31 mmol/L


Clinical Significance
Methylmalonic Acid (MMA) is useful to diagnose and monitor Vitamin B12 (cobalamin) deficiency, and to diagnose and monitor patients with methylmalonic acidemia.


Performing Laboratory
Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano, CA 92675-2042



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.