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Coccidioides Panel w/IMDF Confirm and Comp Fix
Test CodeCOCCI/CF
Alias/See Also
Performed at SQL, test code 1061
Coccidioides EIA (IgM and IgG) with reflex to Immunodiffusion (IMDF) and Complement Fixation
Coccidioides EIA (IgM and IgG) with reflex to Immunodiffusion (IMDF) and Complement Fixation
CPT Codes
86635 x2
Preferred Specimen
1.5 mL serum from a serum separator tube (SST)
Minimum Volume
0.75 mL
Instructions
Centrifuge as soon as possible after clot formation
See link below for specimen details, methodology, setup schedule and reference ranges.
See link below for specimen details, methodology, setup schedule and reference ranges.
Transport Temperature
Refrigerated
Specimen Stability
Ambient: 24 hours
Refrigerated: 5 days
Frozen: 30 days
Refrigerated: 5 days
Frozen: 30 days
Methodology
Enzyme Immunoassay (EIA)
Setup Schedule
Evening shift: Monday through Friday
Night shift: Monday through Sunday
Night shift: Monday through Sunday
Report Available
Available in 1-3 days
Reference Range
Nonreactive
Clinical Significance
Coccidioidomycosis, also known as San Joaquin Valley fever, is a systemic fungal infection endemic to Arizona and other parts of the southwestern United States. Approximately 60% of infections are asymptomatic.Of the 40% who develop symptoms, most will have an acute febrile "flu-like" illness starting 7-28 days (average 10-16 days) after exposure and most patients will recover completely. The main symptoms are fever, pleuritic chest pain, cough, malaise, headache, myalgia, night sweats and loss of appetite. Five percent of patients may develop metapulmonary dissemination to the meninges, bones, joints and subcutaneous and cutaneous tissues, within the first few weeks to months after the onset of primary infection.
This screening panel includes a qualitative antibody test for IgM and IgG. Reactive results will be confirmed via immunodiffusion (at an additional charge). Positive immunodiffusion results will reflex to complement fixation. Complement Fixation (CF), a quantitative IgG assay, is useful as a prognostic test. Results are expressed as titers, such as 1:2 or 1:8. A titer of 1:16 or greater has been frequently associated with extrapulmonary dissemenation. Positive samples are stored frozen for six months while negative samples are stored frozen for one month.
This screening panel includes a qualitative antibody test for IgM and IgG. Reactive results will be confirmed via immunodiffusion (at an additional charge). Positive immunodiffusion results will reflex to complement fixation. Complement Fixation (CF), a quantitative IgG assay, is useful as a prognostic test. Results are expressed as titers, such as 1:2 or 1:8. A titer of 1:16 or greater has been frequently associated with extrapulmonary dissemenation. Positive samples are stored frozen for six months while negative samples are stored frozen for one month.
Performing Laboratory
Sonora Quest Laboratories
Additional Information
Coccidioides Panel w/IMDF Confirm and Comp Fix
Coccidioides Panel w/IMDF Confirm and Comp Fix
Coccidioides Panel w/IMDF Confirm and Comp Fix
Coccidioides Panel w/IMDF Confirm and Comp Fix
Coccidioides Panel w/IMDF Confirm and Comp Fix
Coccidioides Panel w/IMDF Confirm and Comp Fix