Corticosterone, LC/MS

Test Code

CORTICOS

Quest Code

6547

Alias/See Also

6547

CPT Codes
82528

Preferred Specimen

1 mL serum

Minimum Volume

0.5 mL

Other Acceptable Specimens

Plasma collected in: EDTA (lavender-top) tube, EDTA (royal blue-top) tube, sodium heparin (green-top) tube

Instructions

Separate serum after clotting. An early morning specimen is preferred.

Transport Temperature

Refrigerated

Specimen Stability

Room temperature: 72 hours
Refrigerated: 14 days
Frozen: 1 year

Methodology
Chromatography/ Mass Spectrometry (LC/MS)

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

Night Sets up 1 day a week.

Reference Range

See Laboratory Report

Clinical Significance

Measurement of corticosterone may help confirm the diagnosis of the very rare aldosterone deficiency disorder, corticosterone methyl oxidase (18-hydroxylase) enzyme deficiency where the ratio of corticosterone to 18-hydroxycosticosterone may be increased.

Performing Laboratory
Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano, CA 92690-6130

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.