Ganglioside GM-1 Antibodies (IgG, IgM), EIA

Test Code

Quest Code

Alias/See Also

CPT Codes
83520 (x2)

Preferred Specimen
1 mL serum

Patient Preparation
Overnight fasting is preferred

Minimum Volume
0.2 mL

Transport Temperature
Refrigerated (cold packs)

Specimen Stability
Room temperature: 48 hours
Refrigerated: 14 days
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Received room temperature

Immunoassay (IA)

Setup Schedule
Night Sets up 2 days a week.

Reference Range
GM-1 Antibody (IgG) <1:800 titer
GM-1 Antibody (IgM) <1:800 titer

IgG, IgM Antibodies to Ganglioside GM1
Normal <1:800
Moderately elevated 1:800-1:3200
Highly elevated ≥1:6400

Clinical Significance
Ganglioside GM-1 Antibody IgG is associated with the Guillain-Barre syndrome, particularly the acute motor axonal neuropathy variant. Antibody IgM is associated with chronic multifocal motor neuropathy.

Performing Laboratory
Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano, CA 92690-6130

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.