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Ganglioside GM-1 Antibodies (IgG, IgM), EIA
Test CodeGM1GM
Quest Code
37093
Alias/See Also
37093
CPT Codes
83520 (x2)
Preferred Specimen
1 mL serum
Patient Preparation
Overnight fasting is preferred
Minimum Volume
0.2 mL
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
Room temperature: 48 hours
Refrigerated: 14 days
Frozen: 30 days
Refrigerated: 14 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Received room temperature
Methodology
Immunoassay (IA)
Setup Schedule
Night Sets up 2 days a week.
Reference Range
GM-1 Antibody (IgG) | <1:800 titer |
GM-1 Antibody (IgM) | <1:800 titer |
IgG, IgM Antibodies to Ganglioside GM1
Normal | <1:800 |
Moderately elevated | 1:800-1:3200 |
Highly elevated | ≥1:6400 |
Clinical Significance
Ganglioside GM-1 Antibody IgG is associated with the Guillain-Barre syndrome, particularly the acute motor axonal neuropathy variant. Antibody IgM is associated with chronic multifocal motor neuropathy.
Performing Laboratory
Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano, CA 92690-6130