| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Hu Antibody Screen with Reflex to Titer and Western Blot
Test CodeHUA
Quest Code
37053
Alias/See Also
37053
CPT Codes
86255
Includes
If Hu Antibody Screen, IFA is positive, then Hu Antibody, WB will be performed at an additional charge (CPT code(s): 84181).
If Hu Antibody, WB is positive, then Hu Antibody Titer will be performed at an additional charge (CPT code(s): 86256).
If Hu Antibody, WB is positive, then Hu Antibody Titer will be performed at an additional charge (CPT code(s): 86256).
Preferred Specimen
0.5 mL serum
Patient Preparation
Overnight fasting is preferred
Minimum Volume
0.2 mL
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 21 days
Refrigerated: 14 days
Frozen: 21 days
Methodology
Immunofluorescence Assay (IFA) • Western Blot (WB)
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Night Set up: 3 days a week.
Report Available
Reports in 4 days.
Reference Range
| Hu Ab Screen, IFA | Negative |
| Hu Ab, WB | Negative |
| Hu Ab Titer | <1:40 |
Clinical Significance
Paraneoplastic Syndrome involves non-metastatic systemic effects that accompany malignant disease. Antineuronal Nuclear Antibody (Anti-Hu) is found in 5-10% of patients with small cell carcinoma of the lung. Anti-Hu is associated with subacute syndrome of encephalomyeloradiculopathy, sensory neuropathy, and autoimmune neuropathy, predominantly affecting the gastrointestinal tract.
Performing Laboratory
Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano, CA 92690-6130
