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Hemoglobinopathy Evaluation
Test CodeHELEC (QNI)
Quest Code
35489
Alias/See Also
Hemoglobin Electrophoresis
35489
35489
CPT Codes
83020, 85014, 85018, 85041
Includes
Hemoglobin A, Hemoglobin F, Hemoglobin A2 (Quant), Hemoglobin S, Hemoglobin C, Hemoglobin E, and any hemoglobin variants
Red Blood Cell Count, Hemoglobin, Hematocrit, MCV, MCH, RDW
Red Blood Cell Count, Hemoglobin, Hematocrit, MCV, MCH, RDW
Preferred Specimen
Whole blood - full 5.0 mL EDTA (Lav. Top) tube
Minimum Volume
1 mL
Other Acceptable Specimens
Whole blood from a full EDTA (tan-top) tube
Instructions
Patient age and ethnicity are necessary for proper interpretation.
Blood transfusions within the last 4 months may affect results.
Note: If drawn with lead testing, EDTA (tan-top) is required.
Blood transfusions within the last 4 months may affect results.
Note: If drawn with lead testing, EDTA (tan-top) is required.
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
Room temperature: 72 hours
Refrigerated: 6 days
Frozen: Unacceptable
Refrigerated: 6 days
Frozen: Unacceptable
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolysis • Clotted
Methodology
Electronic Sizing and Counting/Cytometry • Capillary Electrophoresis followed by, if necessary, High Performance Liquid Chromatography (HPLC)
Setup Schedule
Set up: Mon-Sat; Report available: 4-6 days
Report Available
4-6 days
Reference Range
See Laboratory Report
Clinical Significance
The detection and proper identification of hemoglobinopathies and thalassemias is an important aspect of the evaluation of patients with anemia, microcytosis and erythrocytosis.
Performing Laboratory
Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano, CA 92690-6130