11-Deoxycortisol

Test Code

DOXCORT11

Quest Code

30543

Alias/See Also

30543

CPT Codes
82634

Preferred Specimen

1 mL serum

Minimum Volume

0.5 mL

Other Acceptable Specimens

Plasma collected in: EDTA (lavender-top) tube, EDTA (royal blue-top) tube, or sodium heparin (green-top) tube

Instructions

Separate serum after clotting. An early morning specimen is preferred.

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

Room temperature: 72 hours
Refrigerated: 14 days
Frozen: 1 year

Methodology
Chromatography/Mass Spectrometry

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

Night Sets up 1 day a week.

Reference Range

See Laboratory Report

Clinical Significance

11-Deoxycortisol (Compound S) is useful in diagnosing patients with 11-beta-hydroxylase deficiency (second leading cause of congenital adrenal hyperplasia) and primary (adrenal failure) or secondary (hypothalamic-pituitary ACTH deficiency) adrenal insufficiency.

Performing Laboratory
Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano, CA 92690-6130

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.