11-Deoxycortisol

Message
Non-Interfaced


Test Code
DOXCORT11


Quest Code
30543


Alias/See Also
30543


CPT Codes
82634

Preferred Specimen
1 mL serum


Minimum Volume
0.5 mL


Other Acceptable Specimens
Plasma collected in: EDTA (lavender-top) • EDTA (royal blue-top) • Sodium heparin (green-top)


Instructions
Separate serum after clotting. An early morning specimen is preferred.


Transport Temperature
Refrigerated (cold packs)


Specimen Stability
Room temperature: 72 hours
Refrigerated: 14 days
Frozen: 1 year


Methodology
Chromatography/Mass Spectrometry

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule
Night Sets up 1 day a week.


Reference Range
See Laboratory Report


Clinical Significance
11-Deoxycortisol (Compound S) is useful in diagnosing patients with 11-beta-hydroxylase deficiency (second leading cause of congenital adrenal hyperplasia) and primary (adrenal failure) or secondary (hypothalamic-pituitary ACTH deficiency) adrenal insufficiency.


Performing Laboratory
Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano, CA 92690-6130



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.