Delta Aminolevulinic Acid, 24-Hour Urine

Test Code

Quest Code

Alias/See Also

CPT Codes

CPT code 81050 may be added at an additional charge for volume measurement

Preferred Specimen
2 mL urine from a 24-hour collection - no preservative - protect from light

Minimum Volume
0.6 mL

Other Acceptable Specimens

Urine preserved with 25 mL 6N HCl or 10 mL concentrated glacial acetic acid • Preservative added after collection • Catheterized urine in a sterile, plastic screw-cap container


Collect without preservative. Refrigerate during and after collection. Wrap container in aluminum foil to protect from light. Please specify on the request form and on the urine container the total 24-hour urine volume.  

Transport Temperature
Refrigerated (cold packs)

Specimen Stability
Room temperature: Unacceptable
Refrigerated: 7 days
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Received room temperature • Not protected from light

Colorimetric (C)

Setup Schedule
P.M. Sets up 2 days a week.

Reference Range
Delta ALA, 24-Hour Urine
Adults <4.5 mg/24 h

Creatinine, 24-Hour Urine
3-8 Years 0.11-0.68 mg/24 h
9-12 Years 0.17-1.41 mg/24 h
13-17 Years 0.29-1.87 mg/24 h
Adults 0.63-2.50 mg/24 h

Clinical Significance
ALA is a precursor to uroporphyrin, coproporphyrin, and protoporphyrin. Concentrations of ALA are greatly increased in many patients with acute neurological forms of porphyrias and in some patients with chronic alcohol abuse.

Performing Laboratory
Quest Diagnostics Chantilly Nichols Institute
14225 Newbrook Dr.
Chantilly, VA 20151-2228

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.