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24 Hour Timed Urine, Histamine
Test CodeTUHIST
Quest Code
4946
Alias/See Also
Histamine, 24-Hour Urine
CPT Codes
83088
Includes
CPT code 81050 may be added at an additional charge for volume measurement
Preferred Specimen
4 mL urine from a 24-hour urine containing 10 mL 6N HCL collected in a leak-proof container
Patient Preparation
Avoid direct sunlight. Patient should refrain from taking allergy causing drugs, antihistamines, oral corticosteroids, and substances which block H2 receptors for at least 24 hours prior to specimen collection.
Minimum Volume
2 mL
Other Acceptable Specimens
Non-preservative 24-hour urine collected in a leak-proof container
Transport Container
Frozen
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
Room temperature: 48 hours
Refrigerated: 14 days
Frozen: 14 days
Refrigerated: 14 days
Frozen: 14 days
Methodology
Immunoassay (IA)
FDA Status
LDT
Setup Schedule
A.M. Sets up 2 days a week.
Reference Range
0.006-0.131 mg/24 h
Clinical Significance
Histamine is a mediator of the allergic response. Histamine release causes itching, flushing, hives, vomiting, syncope, and even shock. In addition, some patients with gastric carcinoids may exhibit high concentrations of histamine.
Performing Laboratory
Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano, CA 92675-2042