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Tropheryma whipplei (Whipple's) DNA, Qualitative, Real-Time PCR
Test CodeTROPWHIPPCRQL
Quest Code
11352X
CPT Codes
87798<br /> <strong>This test is not available for New York patient testing.</strong>
Preferred Specimen
3 mm x3 fresh (unfixed) tissue
Minimum Volume
1 mm x3 tissue • 0.3 mL CSF or whole blood
Other Acceptable Specimens
0.7 mL CSF collected in a sterile vial or whole blood collected in an EDTA (lavender-top) or ACD (yellow-top) tube
Transport Temperature
Tissue: Frozen
CSF and whole blood: Refrigerated (cold packs)
CSF and whole blood: Refrigerated (cold packs)
Specimen Stability
Tissue and CSF
Room temperature: 48 hours
Refrigerated: 7 days
Frozen: 30 days
Whole blood
Room temperature: 48 hours
Refrigerated: 7 days
Frozen: Do Not Freeze
Room temperature: 48 hours
Refrigerated: 7 days
Frozen: 30 days
Whole blood
Room temperature: 48 hours
Refrigerated: 7 days
Frozen: Do Not Freeze
Methodology
Real-Time Polymerase Chain Reaction (RT-PCR)
Setup Schedule
Set up: Mon-Sat; Report available: 1-2 days
Reference Range
Not detected
Clinical Significance
Tropheryma whipplei (Whipple's disease) DNA, PCR is a highly sensitive and specific method to detect the presence of Tropheryma whipplei DNA in clinical specimens. The diagnosis of Tropheryma whipplei infection should not rely solely upon the result of a PCR assay. A positive result should be considered in conjunction with clinical presentation and additional established clinical tests. Moreover, this assay cannot differentiate between viable and nonviable organisms. A negative PCR result indicates the absence of Tropheryma whipplei DNA at detectable levels in the samples tested and does not exclude the diagnosis of disease.
Performing Laboratory
Quest Diagnostics Nichols Institute-San Juan Capistrano, CA |
33608 Ortega Highway |
San Juan Capistrano, CA 92675-2042 |