Amino Acid Analysis, Plasma

Test Code

AAQT FULL

Quest Code

767

CPT Codes
82139

Includes

1-Methylhistidine, 3-Methylhistidine, Alanine, Alpha-Aminoadipic Acid, Alpha-Aminobutyric Acid, Arginine, Asparagine, Aspartic Acid, Beta-Alanine, Beta-Aminoisobutyric Acid, Citrulline, Cystathionine, Ethanolamine, Gamma-Aminobutyric Acid, Glutamic Acid, Glutamine, Glycine, Histidine, Homocystine, Hydroxyproline, Isoleucine, Leucine, Lysine, Methionine, Ornithine, Phenylalanine, Proline, Sarcosine, Serine, Taurine, Threonine, Tryptophan, Tyrosine, Valine

Preferred Specimen

2 mL plasma collected in a sodium heparin (green-top) tube

Patient Preparation
Collect plasma specimens after an overnight fast (or at least 4 hours after a meal). Non-fasting samples are acceptable for pediatric patients

Minimum Volume

0.25 mL

Other Acceptable Specimens

Plasma collected in: EDTA (lavender-top) or lithium heparin (green-top) tube

Instructions

Plasma should be separated from cells as soon as possible after collection. Freeze plasma below -20°C. Patient age is required for correct reference range. Include date of collection and age of patient. (Age must be provided for the interpretation and age related reference ranges to print on the report.

Transport Temperature

Frozen

Specimen Stability

Room temperature: Unacceptable
Refrigerated: 7 days
Frozen: 28 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Gross hemolysis • Received room temperature

Methodology

Chromatography/Mass Spectrometry

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

Set up: Mon-Sat; Report available: 4 days

Reference Range

See Laboratory Report

Clinical Significance

Amino Acid analysis is necessary for the diagnosis of a variety of inborn errors of metabolism. These include, but are not limited to, phenylketonuria, tyrosinemia, citrullinemia, non-ketotic hyperglycinemia, maple syrup urine disease, and homocystinuria. The assay is also key for the continued monitoring of treatment plans for these disorders and useful for assessing nutritional status of patients. Our methodology is highly accurate at very low levels as well as at elevated levels.

Performing Laboratory
Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano, CA 92675-2042

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.