Creatinine Clearance, Timed Urine with Plasma or Serum

Message
Plasma/Serum and Urine are required.


Test Code
CRCLA - NOCO


CPT Codes
82565, 82575

Preferred Specimen
1 mL plasma from Green top (Lithium Heparin)
AND
Entire specimen or 10 mL well mixed aliquot from 24 hour Urine Collection


Minimum Volume
0.5 mL plasma or serum
0.5 mL urine


Other Acceptable Specimens
1 mL serum from SST or Red Top


Instructions
  • Plasma/Serum must be obtained within 12 hours of the collection of urine.
  • Height and Weight are required for processing.
  • Collect urine for 24 hours.
  • Refrigerate specimen during collection.
  • Starting and ending times of collection are required for processing.
  • Total Volume is required for processing.
24 Hour Urine Collection Instructions - English / Spanish


Specimen Stability
Temperature Time
Refrigerated - Serum 5 days
Refrigerated - Urine 5 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis


Methodology
Bichromatic Rate

Setup Schedule
Monday through Sunday; Continuously


Report Available
Same day


Reference Range
            Male
                        0-6 months: 50 – 75 mL/min
                        6-18 months: 50 – 110 mL/min
                        18 months – 150 years: 85 – 125mL/min
            Female
                        0-6 months: 50 – 75 mL/min
                        6-18 months: 50 – 110 mL/min
                        18 months – 150 years: 75 – 115mL/min


Clinical Significance
Creatinine is an endogenous substance most commonly used to measure the glomerular filtration rate (GFR) of the
kidneys. The linear decrease of creatinine clearance over time, as renal function fails, has been thoroughly documented
for several forms of chronic glomerulonephritis (including chronic membranous glomerular nephritis, diabetic
nephropathy, chronic interstitial nephritis, and at least some cases of chronic pyelonephritis).


Performing Laboratory
Banner Fort Collins Medical Center Laboratory
Mckee Medical Center Laboratory
North Colorado Medical Center Laboratory



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.