A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Protein, Total, Plasma or Serum
Test CodeProtein Total Serum/PROT - NOCO
CPT Codes
84155
Includes
Note: This test is included in CMPGFR - Comprehensive Metabolic Panel and HFP - Hepatic Function Panel
Preferred Specimen
1 mL plasma from Green top (Lithium Heparin)
Minimum Volume
0.5 mL
Note: For neonate requirements see Neonate Minimum Blood Volumes
Note: For neonate requirements see Neonate Minimum Blood Volumes
Other Acceptable Specimens
1 ml serum from Serum Gel or Red Top
Specimen Stability
Specimen Type | Temperature | Time |
Plasma Li Hep | Refrigerated | 72 hours |
Serum SST | Refrigerated | 72 hours |
Red Top – Separated* | Refrigerated | 72 hours |
*Centrifuge and aliquot into a plastic vial.
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis
Methodology
Colorimetric Bichromatic Endpoint, Biuret
Setup Schedule
Monday through Sunday; Continuously
Report Available
Same day
Reference Range
0 - 31 days: 4.1 - 6.3 g/dL
31 days - 6 months: 4.7 - 6.7 g/dL
6 months - 1 year: 5.5 - 7.0 g/dL
1 - 18 years: 5.4 - 7.6 g/dL
18 - 150 years: 6.0 - 8.0 g/dL
31 days - 6 months: 4.7 - 6.7 g/dL
6 months - 1 year: 5.5 - 7.0 g/dL
1 - 18 years: 5.4 - 7.6 g/dL
18 - 150 years: 6.0 - 8.0 g/dL
Clinical Significance
Plasma proteins are synthesized predominately in the liver, plasma cells, lymph nodes, the spleen and in bone marrow. In the course of disease the total protein concentration and also the percentage represented by individual fractions can significantly deviate from normal values. Hypoproteinemia can be caused by diseases and disorders such as loss of blood, sprue, nephrotic syndrome, severe burns, salt retention syndrome and Kwashiorkor (acute protein deficiency). Hyperproteinemia can be observed in cases of severe dehydration and illnesses such as multiple myeloma. Changes in the relative percentage of plasma proteins can be due to a change in the percentage of one plasma protein fraction. Often in such cases the amount of total protein does not change. The A/G ratio is commonly used as an index of the distribution of albumin and globulin fractions. Marked changes in this ratio can be observed in cirrhosis of the liver, glomerulonephritis, nephrotic syndrome, acute hepatitis, lupus erythematosus as well as in certain acute and chronic inflammations. Total protein measurements are used in the diagnosis and treatment of a variety of diseases involving the liver, kidney, or bone marrow, as well as other metabolic or nutritional disorders
Performing Laboratory
Banner Fort Collins Medical Center Laboratory
McKee Medical Center Laboratory
North Colorado Medical Center Laboratory
Summit View Laboratory