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Calcium, Ionized, Blood
MessageRecommend collection at a hospital testing site only due to method testing time constraints.
Specimen must be tested within 1 hour of draw.
Specimen must be tested within 1 hour of draw.
Test Code
Calcium, Ionized/ICA - NOCO
Alias/See Also
Ionized Calcium
CPT Codes
82330
Preferred Specimen
Green top (Lithium Heparin) (can have gel - Do Not spin)
Minimum Volume
2 mL
Other Acceptable Specimens
Heparin blood gas syringe Specimen
- Cap syringe(s) tightly, remove any air bubbles, immediatley place on crushed ice.
Instructions
Transport to lab on crushed ice.
Methodology
Potentiometric
Setup Schedule
Monday through Sunday; Continuously
Report Available
Same day
Reference Range
4.5-5.1 mg/dL
Critical value (automatic call-back): <3.3 or >6.0 mg/d
Critical value (automatic call-back): <3.3 or >6.0 mg/d
Clinical Significance
Ionized calcium measurements are used in the diagnosis, monitoring, and treatment of conditions including, but
not limited to, parathyroid disease, a variety of bone diseases, chronic renal disease, tetany, and disturbances
related to surgical and intensive care.
Measurements of ionized calcium have proven of value under the following clinical conditions: transfusion of
citrated blood, liver transplantation, open heart surgery, neonatal hypocalcemia, renal disease,
hyperparathyroidism, malignancy, hypertension and pancreatitis.
Although most of the calcium in blood is bound to protein or complexed to smaller anionic species, the biologically
active fraction of calcium is free ionized calcium. Through its role in a number of enzymatic reactions and in
membrane transport mechanisms, ionized calcium is vitally important in blood coagulation, nerve conduction,
neuromuscular transmission and in muscle contraction.
not limited to, parathyroid disease, a variety of bone diseases, chronic renal disease, tetany, and disturbances
related to surgical and intensive care.
Measurements of ionized calcium have proven of value under the following clinical conditions: transfusion of
citrated blood, liver transplantation, open heart surgery, neonatal hypocalcemia, renal disease,
hyperparathyroidism, malignancy, hypertension and pancreatitis.
Although most of the calcium in blood is bound to protein or complexed to smaller anionic species, the biologically
active fraction of calcium is free ionized calcium. Through its role in a number of enzymatic reactions and in
membrane transport mechanisms, ionized calcium is vitally important in blood coagulation, nerve conduction,
neuromuscular transmission and in muscle contraction.
Performing Laboratory
Banner Fort Collins Medical Center Laboratory
McKee Medical Center Laboratory
North Colorado Medical Center Laboratory
