Epstein-Barr Virus Panel

Test Code
EBV


Alias/See Also
Performed at SQL, test code 2955
Epstein Barr Virus (EBV) Panel


CPT Codes
86665x2, 86664

Includes
EBV to Viral Capsid Antigen, IgG
EBV to Viral Capsid Antigen, IgM
EBV Ab to Nuclear Antigen, IgG


Instructions
See link below for specimen details, methodology, setup schedule and reference ranges.


Clinical Significance
Primary infection by EBV causes infectious mononucleosis, usually a self-limiting disease in children and young adults. Infection with EBV can cause lymphoproliferative disorders including tumors.

Epstein-Barr Virus (EBV) Panel consists of the following EBV-associated antigens: EBV to Viral Capsid Antigen (VCA), IgG; EBV to Viral Capsid Antigen, IgM; and EBV Ab to Nuclear Antigen (EBNA), IgG. 

VCA-IgM is typically detectable at clinical presentation, then declines to undetectable levels within a month in young children and within 3 months in other individuals. VCA-IgG is typically detectable at clinical presentation, and persists for life. EBNA IgG typically appears during convalescence (3-4 months after clinical presentation) and remains detectable for life.


Additional Information
Epstein-Barr Virus (EBV) Panel


The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.