Aldosterone, 24-Hour Urine (19552X)

Message

Non-Interface
Place order in Quanum to include total volume

Test Code

ALDOSTU

Quest Code

7062N

Alias/See Also

Aldosterone 18-Glucuronide

CPT Codes
82088

Includes

Creatinine

CPT code 81050 may be added at an additional charge for volume measurement

Preferred Specimen

1.5 mL 24-hour urine collected in a 24-hour container

Minimum Volume

0.8 mL

Other Acceptable Specimens

24-hour urine collected in a 24-hour urine container with 10g boric acid • Random urine collected in a no preservative container (Reference ranges do not apply)

Instructions

Record 24-hour urine volume on test requisition and urine vial. Refrigerate during and after collection.
Reference ranges do not apply to random urine samples.

Transport Container

Transport tube

Transport Temperature

Refrigerated

Specimen Stability

Room temperature: 7 days
Refrigerated: 28 days
Frozen: 21 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Urine collected with HCl

Methodology
Hydrolysis • Extraction • Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

Night Sets up 2 days a week.

Report Available

Max Lab time 10 days

Reference Range

Aldosterone, 24-Hour Urine
Random Sodium Diet

Age	mcg/24 hours
2-7 years	5.7 or less
8-11 years	10.2 or less
12-16 years	15.6 or less
Adults	2.3-21.0

Oral sodium loading test (high salt diet for 3 days): 12 mcg/24 hrs or less*

*Funder JW, Carey RM, Mantero F, et al. The Management of Primary
Aldosteronism: Case Detection, Diagnosis, and Treatment: An Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab. 2016; 101:1889-1916

Creatinine, 24-Hour Urine

<3 Years	Not established
3-8 Years	0.10-0.80 g/24 h
9-12 Years	0.20-1.40 g/24 h
13-17 Years	0.40-1.90 g/24 h
>17 Years	0.50-2.15 g/24 h

Clinical Significance

Aldosterone is a hormone produced by the adrenal glands. Patients with primary hyperaldosteronism exhibit hypokalemia, hypertension, and low direct renin concentrations.

Performing Laboratory
Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano, CA 92690-6130

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.