A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Rubella Antibody (IgM)
Test CodeRUBIGM
Quest Code
4422X
Alias/See Also
4422X
CPT Codes
86762
Preferred Specimen
1 mL serum
Minimum Volume
0.6 mL
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 4 days
Refrigerated: 7 days
Frozen: 30 days
Refrigerated: 7 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly lipemic
Methodology
Immunoassay (IA)
Setup Schedule
Set up: Mon, Tues, Thurs-Sat; Report available: 1-3 days
Report Available
Maximum Laboratory Turn Around Time 4 days.
Reference Range
AU/mL | Interpretation |
<20.00 | Negative |
20.00-24.99 | Equivocal |
≥25.00 | Positive |
Clinical Significance
Rubella is an acute exanthematous viral infection of children and adults. Rash, fever and lymphadenopathy characterize the illness. While many infections are subclinical, this virus has the potential to cause fetal infection with resultant birth defects. In the absence of a current or recent infection, a demonstration of specific IgG on a serum sample is evidence of immunity to rubella. A positive rubella IgM result does not necessarily indicate current or recent infection. Without a history of exposure to rubella or symptoms consistent with rubella, the IgM result may be difficult to interpret. Rubella IgM can be false positive due to other causes (e.g., parvovirus, rheumatoid factor, cytomegalovirus). Rubella IgM may also persist for more than 12 months after vaccination or natural infection. For a serologic diagnosis of congenital rubella in the neonatal period, antibody to rubella virus should be measured in both infant and maternal sera. If IgM is detected in a newborn infants serum, it is probable that transplacental rubella infection has occurred.
Performing Laboratory
Quest Diagnostics Nichols Institute |
33608 Ortega Highway |
San Juan Capistrano, CA 92675-2042 |