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Hepatitis B Core Ab, Igm
MessageNCMC does not perform hepatitis testing on cadaver samples.
Test Code
HBCABM - NCMC
CPT Codes
86705
Preferred Specimen
1 mL plasma from light green top (lithium heparin)
Minimum Volume
0.5 mL
Other Acceptable Specimens
1 mL serum from SST or Red Top
Instructions
1 mL serum from SST or Red Top
Specimen Stability
| Specimen Type | Temperature | Time |
| Serum SST | Refrigerated | 2 days |
| Serum SST – Separated | Frozen | 30 days |
| Red Top – Separated* | Refrigerated | 2 days |
| Red Top – Separated* | Frozen | 30 days |
*Centrifuge and aliquot into a plastic vial.
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis, icterus, lipemia
Methodology
Capture immunoassay
Setup Schedule
Monday through Sunday; Continuously
Report Available
Same day
Reference Range
Nonreactive
(reported as Nonreactive, Equivocal or Reactive)
All Equivocal should be retested on new specimen.
(reported as Nonreactive, Equivocal or Reactive)
All Equivocal should be retested on new specimen.
Clinical Significance
Hepatitis B Core Antibodies appear at the onset of symptoms in acute hepatitis B and persist for life. The presence of anti-HBc indicates previous or ongoing infection with hepatitis B virus in an undefined time frame. Hep B Core IgM positivity indicates recent infection with hepatitis B virus (<6 mos).
HBV vaccination leads to development of HBs Ab but not to HBc Ab. Anti-Hbc IgG reactivity can persist for years after illness, and may even outlast anti-HBS.
HBV vaccination leads to development of HBs Ab but not to HBc Ab. Anti-Hbc IgG reactivity can persist for years after illness, and may even outlast anti-HBS.
Performing Laboratory
North Colorado Medical Center Laboratory
