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Bilirubin - Direct

Message
Bilirubin is an end product of hemoglobin catabolism.  It is conjugated with glucuronic acid in the liver, and the conjugated form is cleared from the circulation by excretion in the bile.  Both conjugated (direct) and unconjugated (indirect) forms of bilirubin circulate loosely bound to albumin.  The assessment of direct bilirubin is helpful in the determination of hepatic disorders.


Test Code
BILID


Alias/See Also
LAB3000025


CPT Codes
82248

Preferred Specimen
2.0 mL serum collected in a gold serum separator tube (SST)


Minimum Volume
0.5 mL serum


Other Acceptable Specimens
2.0 mL serum collected in an orange rapid clot serum separator tube (RCT)
2.0 mL plasma collected in a light green lithium heparin plasma separator tube (PST)


Instructions
Protect from light as soon as possible.


Specimen Stability
When well protected from light, bilirubin in serum is stable for up to three days refrigerated (2 - 8oC) and approximately three months when stored <=-20oC


Methodology
Variation of the classical method developed by Van den Bergh and Mueller

Reference Range
 
Sex Age Reference Range
M/F 0 - 6 days 0 - 0.6 mg/dL
M/F 7 days - 150 years 0 - 0.2 mg/dL


Performing Laboratory
Penn Medicine Lancaster General Health



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.