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Intrinsic Factor Blocking Antibody
Test Code568
Alias/See Also
ZG329
Intrinsic Factor Blocking Ab
LAB3020647
Intrinsic Factor Blocking Ab
LAB3020647
CPT Codes
86340
Preferred Specimen
1.0 mL serum collected in a gold serum separator tube (SST)
Minimum Volume
0.3 mL
Instructions
Samples should not be collected from a patient who has received vitamin B12 injection therapy within the past week.
Transport Container
Transport tube
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 7 days
Refrigerated: 7 days
Frozen: 28 days
Refrigerated: 7 days
Frozen: 28 days
Methodology
Immunoassay (IA)
Setup Schedule
Set up: Tues-Sat; Report available: 2-3 days
Reference Range
Negative
Clinical Significance
Intrinsic Factor, produced by cells lining the stomach, binds Vitamin B12 (cyanocobalamin) to facilitate absorption of the vitamin. Blocking antibody impedes the action of Intrinsic Factor as observed in approximately half of the patients who develop pernicious anemia.
