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Cryoglobulin (% Cryocrit), Serum
MessageMust be collected only at the following location:
Duke Street Lab Testing
Holiday collection guideline:
Due to short specimen stability, specimens collected the day before a holiday must be received in the laboratory by 1500 to ensure testing is performed by reference laboratory.
Duke Street Lab Testing
Holiday collection guideline:
Due to short specimen stability, specimens collected the day before a holiday must be received in the laboratory by 1500 to ensure testing is performed by reference laboratory.
Test Code
36562
Alias/See Also
CRYQ
LAB0001262
LAB0001262
CPT Codes
82595
Preferred Specimen
3 mL serum collected in a red-top tube (no gel)
Minimum Volume
2 mL
Instructions
Allow blood to clot for one (1) hour in a 37° C water bath, incubator, heat block, or heel warmer. After clotting, centrifuge the specimen as quickly as possible. It is not necessary to use a warm centrifuge but do not use a refrigerated one. Decant all of the serum into one screw-cap vial (do not aliquot any of the cryoglobulin serum into any other tube). Transport at room temperature.
Note: If the sample is not kept at 37° C during clotting, the cryoglobulin, if present, can precipitate during centrifugation and be lost in the clot resulting in a false negative result.
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 14 days
Refrigerated: 14 days
Frozen: 30 days
Refrigerated: 14 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly lipemic • Icteric • Serum separator tube (SST)
Methodology
Visual Inspection
Setup Schedule
Set up: Daily; Report available: 5-7 days
Report Available
The Cryocrit is primarily intended for following a patient with previously defined and quantitated cryoglobulins. The cryocrit may consist of cryoglobulins, fibrins or mixtures of cryoglobulins and fibrins. If not previously characterized, consider ordering Cryoglobulin Screen with Reflex to Cryoglobulin Profile, Serum
Reference Range
| Cryoglobulin Qualitative | Negative |
| % Cryocrit | None detected |
Clinical Significance
The cryocrit is primarily intended for following a patient with previously defined and quantitated cryoglobulins. The cryocrit may consist of cryoglobulins, fibrins or mixtures of cryoglobulins and fibrins. If not previously characterized, consider ordering Cryoglobulin Screen with Reflex to Cryoglobulin Profile, Serum.
