A B C D E F G H I J K L M N O P Q R S T U V W X Y Z #

Tacrolimus

Message
The assay is used as an aid in the management of liver and kidney transplant patients receiving tacrolimus therapy.


Test Code
FK506


Alias/See Also
LAB3001798
FK506 Transplant Levels


CPT Codes
80197

Preferred Specimen
4.0 mL whole blood collected in a K2 EDTA lavender top tube


Minimum Volume
0.5 mL whole blood


Specimen Stability
Specimens may be stored up to 5 days at room temperature (15 - 25oC) or at 7 days refrigerated (2 - 8oC).  If needed, samples may be frozen a at -20oC or lower for up to 3 months.


Methodology
Immunoassay

Setup Schedule
Batched, started daily around 1100


Report Available
Within 3 hours of batch start


Limitations
High dose Biotin Supplementation can cause falsely increased or decreased results. 


Reference Range
No definitive therapeutic or toxic ranges have been 
established. Target steady-state concentrations vary depending 
on several factors, including the type of transplant, patient 
response, concomitant immunosuppression, clinical/institutional 
protocols, and time post-transplant. Results should be 
interpreted in conjunction with this clinical information and 
any physical signs or symptoms of rejection or toxicity.

Specimens from patients who are undergoing biotin therapy
and/or taking biotin supplements may contain high levels of
biotin. High levels of biotin in specimens may cause falsely
high results.


Performing Laboratory
Penn Medicine Lancaster General Health



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.