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Cancer Antigen 19-9

Message
Initially found in colorectal cancer patients, the CA 19-9 antigen has also been identified in patients with pancreatic, bile duct, hepatocellular, stomach, and esophageal cancers.  Non-cancerous conditions that may elevate CA 19-9 antigen levels include cirrhosis, cholangitis, hepatitis, pancreatitis,and non-malignant gastrointestinal diseases.


Test Code
CA199


Alias/See Also
LAB0001422
CA19-9


CPT Codes
86301

Preferred Specimen
2.0 mL serum collected in a gold serum separator tube (SST)


Minimum Volume
0.5 mL serum


Other Acceptable Specimens
2.0 mL serum collected in an orange rapid clot serum separator tube (RCT)


Specimen Stability
Store centrifuged samples tightly stoppered at room temperature 15 - 30oC for no longer than eight hours.  If the assay will not be completed within eight hours, refrigerate the samples at 2 - 8oC.  If the assay will not be completed within 48 hours, or for shipment of samples, freeze serum at -20oC or colder.


Methodology
Two-site immunoenzymatic ("sandwich") assay

Limitations
High dose Biotin Supplementation can cause falsely increased or decreased results. 


Reference Range
 
Sex Age Reference Range
M/F 0 - 150 years 0 - 35 U/mL


Performing Laboratory
Penn Medicine Lancaster General Health



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.