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Escitalopram, Serum/Plasma
Test Code15857
CPT Codes
80299
Preferred Specimen
1 mL serum collected in a red-top tube (no gel), or 1 mL plasma collected in an EDTA (lavender-top) tube, or an EDTA (pink-top) tube
Minimum Volume
0.4 mL
Instructions
Promptly centrifuge and separate serum or plasma into a plastic, screw-capped vial, using approved guidelines.
Transport Container
Transport tube
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 30 days
Refrigerated: 30 days
Frozen: 7 months
Refrigerated: 30 days
Frozen: 7 months
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Serum separator tube (SST) • PST
Methodology
High Performance Liquid Chromatography/Tandem Mass Spectrometry (HPLC-MS/MS)
FDA Status
This test was developed and its performance characteristics determined by NMS Labs. It has not been cleared or approved by the US Food and Drug Administration.
Setup Schedule
Set up: As needed; Report available: 4 days
Reference Range
Steady-state serum or plasma levels from patients on a daily regimen of 30 to 60 mg Citalopram: 9-200 ng/mL.
Steady-state peak plasma levels from patients on regimen of 10 or 30 mg/day: 21 and 64 ng/mL, respecitvely, and occur at approximately 4 hours post dose.
This test is not chiral specific; therefore, Citalopram and/or Escitalopram may be present. Patients who have taken Racemic Citalopram (Celexa®), as opposed to Escitalopram (Lexapro®), within the past 3 days may have falsely elevated values.
Analysis by High Performance Liquid Chromatography/Tandem Mass Spectrometry (LC-MS/MS).
Performing Laboratory
NMS Labs
200 Welsh Rd
Horsham, PA 19044