Tyrosinase, IHC with Interpretation

Test Code

CPT Codes

Preferred Specimen
Formalin-fixed, paraffin-embedded tissue block submitted in an IHC specimen transport kit

Minimum Volume
3 slides

Other Acceptable Specimens
3 unstained, positively (+) charged slides

Please include surgical pathology report.

Transport Temperature
Room temperature

Specimen Stability
Room temperature: Indefinitely
Refrigerated: Indefinitely
Frozen: Unacceptable


Setup Schedule
Set up: Mon-Fri; Report available: 3 days

Reference Range
Interpretive report

Clinical Significance
Tyrosinase, an enzyme that mediates melanin pigment biosynthesis, is immunoreactive in amelanotic and melanotic tumors. Tyrosinase is also one of the common targets of immunoreactive lymphocytes in melanoma.

Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.