InScape® p53 Oncoprotein, Quantitative IHC without Interpretation

Test Code

16236

CPT Codes
88361-TC

Preferred Specimen

Formalin-fixed, paraffin-embedded tissue block

Other Acceptable Specimens

Minimum: 3 unstained, positively charged slides

Transport Container

IHC Specimen Transport Kit

Transport Temperature

Room temperature

Specimen Stability

Room temperature: Indefinitely
Refrigerated: Indefinitely
Frozen: Unacceptable

Methodology
Immunohistochemistry (IHC)

Setup Schedule

Set up: Mon-Fri; Report available: Next day

Clinical Significance

The result of this immunohistochemical study is reported as a percent of tumor nuclei that demonstrate moderate or strong immunoreactivity. Various published studies have suggested that overexpression of p53 protein in breast cancer may be an unfavorable prognostic indicator. For other types of tumors, definitive interpretive criteria for p53 expression may vary.

Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.