InScape® p53 Oncoprotein, Quantitative IHC without Interpretation

Test Code
16236


CPT Codes
88361-TC

Preferred Specimen
Formalin-fixed, paraffin-embedded tissue block


Other Acceptable Specimens
Minimum: 3 unstained, positively charged slides


Transport Container
IHC Specimen Transport Kit


Transport Temperature
Room temperature


Specimen Stability
Room temperature: Indefinitely
Refrigerated: Indefinitely
Frozen: Unacceptable


Methodology
Immunohistochemistry (IHC)

Setup Schedule
Set up: Mon-Fri; Report available: Next day


Clinical Significance
The result of this immunohistochemical study is reported as a percent of tumor nuclei that demonstrate moderate or strong immunoreactivity. Various published studies have suggested that overexpression of p53 protein in breast cancer may be an unfavorable prognostic indicator. For other types of tumors, definitive interpretive criteria for p53 expression may vary.


Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.