Doxycycline

Test Code

94093

CPT Codes
80299<br><strong>This test is not available for New York patient testing</strong>

Preferred Specimen

1 mL serum collected in a red-top tube (no gel)

Minimum Volume

0.5 mL

Instructions

Specimens collected just before or within 15 minutes of the next antibiotic dose represent the trough level.
Specimens obtained within 15-30 minutes after the end of IV infusion, or 45-60 minutes after an IM injection, or 90 minutes after oral intake represent the peak level

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

Room temperature: 7 days
Refrigerated: 7 days
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Serum separator tubes (SST) • Other body fluids

Methodology
Chromatography/Mass Spectrometry

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

Set up: Wed, Sat; Report available: 1-5 days

Reference Range

Therapeutic range

1-10 mcg/mL

Be cautious with toxic effects when doxycycline level is over 30 mcg/mL. Interpretation of results should include clinical evaluation.

Clinical Significance

The concentration of antimicrobial agents in body fluids, most notably serum or plasma, are used to regulate therapy to ensure effective dosing (especially with oral agents where GI absorption is in question), to monitor accumulation to help minimize toxicity, and to help evaluate the pharmacokinetics of new agents. Both peak and trough levels obtained immediately after dosing or immediately prior to new dosing, respectively, may be monitored.

Performing Laboratory
Quest Diagnostics Lewisville
2501 South State Highway 121
Suite 1100
Lewisville, TX 75067-8188

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.