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Hepatocellular Carcinoma Panel
Test Code16222
CPT Codes
82107, 83951
Includes
Alpha-Fetoprotein (AFP), AFP-L3, DCP (Des-Gamma-Carboxy-Prothrombin)
Preferred Specimen
2 mL serum
Minimum Volume
1 mL
Transport Container
Plastic screw-cap vial
Transport Temperature
Frozen
Specimen Stability
Room temperature: 48 hours
Refrigerated: 5 days
Frozen: 21 days
Refrigerated: 5 days
Frozen: 21 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolysis • Lipemia • Heavy, visible particulate matter • Icteric
Methodology
Liquid-Phase Binding Assay System • Immunoassay (IA)
Setup Schedule
Setup: Tues; Report available: 3 days
Reference Range
AFP | 1.6-4.5 | ng/mL | ||
AFP-L3 | 0.5-9.9 | % | ||
DCP | <7.5 | ng/mL |
Clinical Significance
HCC Risk Panel includes serum AFP-L3%, total AFP and DCP. The combined measurement helps discriminate benign and malignant conditions related to primary liver diseases [1-4]. Furthermore, the combination measurement of three HCC biomarkers can identify a greater number of patients at risk of developing HCC than with each marker alone.
Performing Laboratory
Quest Diagnostics Nichols Institute-San Juan Capistrano, CA |
33608 Ortega Highway |
San Juan Capistrano, CA 92675-2042 |