A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
HIV-1 Resistance, Proviral DNA (RT, PI Inhibitors)
Test Code94808
CPT Codes
87900, 87901
Preferred Specimen
2 mL whole blood collected in an EDTA (lavender-top) tube
Minimum Volume
0.6 mL
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 7 days
Refrigerated: 7 days
Frozen: 28 days
Refrigerated: 7 days
Frozen: 28 days
Methodology
Polymerase Chain Reaction (PCR) • Next Generation (ultra-deep) Sequencing
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics Infectious Disease. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Set up: Tues, Sat; Report available: 6-8 days
Reference Range
See Laboratory Report
Clinical Significance
This test utilizes PCR and next generation (ultra-deep) sequencing of proviral DNA to detect drug resistance mutations in the HIV-1 protease and reverse transcriptase genes. This information will assist clinicians considering a modification of the treatment regimens for virologically suppressed patients or for patients with a low viral load for whom an RNA resistance test was not successful.
Performing Laboratory
Quest Diagnostics Nichols Institute-San Juan Capistrano, CA |
33608 Ortega Highway |
San Juan Capistrano, CA 92675-2042 |