InScape(R) ER, Quant. IHC w/Interpretation [70183X]

Test Code
70183


CPT Codes
*ERRO (x0)

Preferred Specimen
1 Block Formalin Fixed Paraffin Block
Instructions: Please include surgical pathology report.

Per ASCO/CAP guidelines, ER (Estrogen Receptor) and PR
(Progesterone Receptor) positivity requires at least 1%
of tumor cells to show positive nuclear staining of any
intensity.
A negative result for ER and PR will be reported if < 1%
of tumor cells show staining.


Minimum Volume
1 Block


Other Acceptable Specimens
3 Slides Unstained, positively charged slides
IHC Specimen Transport Kit; Room Temperature;

Stability:
__Room Temperature: Indefinitely
__Refrigerated: Indefinitley
__Frozen: Do Not Freeze


Transport Container
IHC Specimen Transport Kit


Transport Temperature
Room Temperature


Specimen Stability
Room Temperature: Indefinitely
Refrigerated: Indefinitely
Frozen: Do Not Freeze


Methodology
Immunohistochemistry (IHC)

Setup Schedule
Monday-Friday Morning
Report available: Next Day


Reference Range
See Medical Report


Clinical Significance
Breast cancer is a heterogeneous disease and there is a continual drive to identify markers that will aid in predicting prognosis and response to therapy. Estrogen receptor (ER) is probably the most powerful predictive marker in breast cancer management, both in determining prognosis and in predicting response to hormone therapies.


Performing Laboratory
Quest Diagnostics Nichols Institute 14225 Newbrook Drive Chantilly, VA 20153



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.