A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Gastrin, 5 Specimens [6723X]
Test Code43112
CPT Codes
82941, 82938 (x4)
Preferred Specimen
1 mL (x5) frozen serum for each timed specimen
Patient Preparation
Overnight fasting (12 hours).
The serum secretin test requires patients to be off of antacids and anticholinergic medications for 12 hours prior to the test. Proton pump inhibitors should not be discontinued because of concern of complications (acute bleeding and/or perforation if acid suppression is discontinued).
Minimum Volume
0.5 mL (x5)
Instructions
Secretin Stimulation: The secretin used is a preparation from RepliGen ((GIH Stimulation). For this protocol, 0.4 mcg of secretin per kilogram of body weight is infused by intravenous bolus. Serum for gastrin is collected at -10 minutes and -1 minute before secretin injection, and +2 minutes, +5, +10, +15, +20, and +30 minutes after secretin stimulation. Label each tube with time of collection.
Dietary supplements containing biotin may interfere in assays and may skew analyte results to be either falsely high or falsely low. For patients receiving the recommended daily doses of biotin, draw samples at least 8 hours following the last biotin supplementation. For patients on mega-doses of biotin supplements, draw samples at least 72 hours following the last biotin supplementation
Dietary supplements containing biotin may interfere in assays and may skew analyte results to be either falsely high or falsely low. For patients receiving the recommended daily doses of biotin, draw samples at least 8 hours following the last biotin supplementation. For patients on mega-doses of biotin supplements, draw samples at least 72 hours following the last biotin supplementation
Transport Container
Plastic screw-cap vial(s)
Transport Temperature
Frozen
Specimen Stability
Room temperature: Unacceptable
Refrigerated: Unacceptable
Frozen: 28 days
Refrigerated: Unacceptable
Frozen: 28 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly lipemic • Grossly icteric • Received thawed
Methodology
Immunoassay
Setup Schedule
Set up: Mon-Sat evening; Report available: 1 day
Reference Range
Reference range applies to fasting specimen only | |
<5 years | Not established |
5-17 years | <65 pg/mL |
≥18 years | ≤100 pg/mL |
Post secretion stimulation response | |
>200 pg/mL above basal level: positive test |
Clinical Significance
For the diagnosis and monitoring of gastrin-secreting tumors, gastric ulcer, Zollinger-Ellison syndrome.
Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153