| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
P57, IHC without Interpretation
Test Code90227
CPT Codes
88342
Preferred Specimen
1 formalin fixed paraffin block
Minimum Volume
1 block • 3 slides
Other Acceptable Specimens
3 Slides Unstained, positively charged slides IHC Specimen Transport Kit
Instructions
Please include surgical pathology report
Transport Temperature
Room temperature
Specimen Stability
Room temperature: Indefinitely
Refrigerated: Indefinitely
Frozen: Do Not Freeze
Refrigerated: Indefinitely
Frozen: Do Not Freeze
Methodology
Immunohistochemistry (IHC)
Setup Schedule
Set up: Mon-Fri; Report available: Next day
Reference Range
See Laboratory Report
Clinical Significance
Immuostaining for p57, a nuclear cell cycle regulator,
can help discriminate between complete hydatidiform mole,
which lacks p57 expression in cytotrophoblasts, from
partial hydatidiform mole and hydropic abortion where p57
expression is intact.
Intervillous trophoblastic islands (IVTIs) demonstrate
nuclear labeling in all three entities and can serve as
an internal control.
can help discriminate between complete hydatidiform mole,
which lacks p57 expression in cytotrophoblasts, from
partial hydatidiform mole and hydropic abortion where p57
expression is intact.
Intervillous trophoblastic islands (IVTIs) demonstrate
nuclear labeling in all three entities and can serve as
an internal control.
Performing Laboratory
| Quest Diagnostics Nichols Institute |
| 14225 Newbrook Drive |
| Chantilly, VA 20153 |
