19911A>G Mutation Analysis

Test Code

16533

CPT Codes
81400

Preferred Specimen

5 mL whole blood collected in an EDTA (lavender-top) tube

Minimum Volume

3 mL

Other Acceptable Specimens

Whole blood collected in: ACD solution A or B (yellow-top) tube, or lithium or sodium heparin (green-top) tube

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 8 days
Refrigerated: 8 days
Frozen: Unacceptable

Methodology
Capillary Electrophoresis • Fluorescence Detection • Polymerase Chain Reaction Amplification • Single Nucleotide Extension

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

Set up: Thurs; Report available: 8 days

Reference Range

See Laboratory Report

Clinical Significance

This test can be used to detect the 19911A→G polymorphism in the prothrombin (Factor II) gene which may modulate the risk of deep vein thrombosis in patients with the G20210A mutation.

Performing Laboratory

Quest Diagnostics Nichols Institute-San Juan Capistrano, CA

33608 Ortega Highway

San Juan Capistrano, CA 92675-2042

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.