Vancomycin, Peak and Trough

Test Code

5406

CPT Codes
80202 (x2)

Preferred Specimen

1 mL serum collected in each of two separate red-top tubes (no gel)

Patient Preparation
Collect peak 1 hour after completion of the drug infusion. Collect as a trough just prior to next dose.

Minimum Volume

0.2 mL for each specimen

Other Acceptable Specimens

Plasma collected in each of two separate: EDTA (lavender-top) tubes, or sodium heparin (green-top) tubes, or lithium heparin (green-top) tubes, or fluoride/potassium oxalate (gray-top) tubes

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 72 hours
Refrigerated: 7 days
Frozen: Unacceptable

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Serum separator tube (SST)

Methodology
Immunoassay (IA)

Setup Schedule

Set up: Mon-Sat; Report available: 1-2 days

Reference Range

	Peak	Trough
Therapeutic	20.0-40.0 mg/L	10.0-20.0 mg/L

Clinical Significance

Vancomycin is an antibiotic used in the treatment of bacterial infections, especially methicillin-resistant staphylococci. Vancomycin is also used in treatment for penicillin-allergic patients who cannot receive or have failed to respond to other drugs, including the penicillins and/or cephalosporins and for other infections caused by vancomycin-susceptible organisms.

Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.