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Tobramycin, Peak
Test Code8576
CPT Codes
80200
Preferred Specimen
1 mL serum collected in a red-top tube (no gel)
Patient Preparation
Collect 30 minutes after end of IV infusion or 60-90 minutes after IM dose.
Minimum Volume
0.2 mL
Other Acceptable Specimens
Plasma collected in: EDTA (lavender-top) tube, or sodium heparin (green-top) tube, or lithium heparin (green-top) tube, or 3.2% sodium heparin (light blue-top) tube, or fluoride/potassium oxalate (gray-top) tube
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 7 days
Refrigerated: 7 days
Frozen: 7 days
Refrigerated: 7 days
Frozen: 7 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Serum separator tube
Methodology
Immunoassay (IA)
Setup Schedule
Set up: Mon-Sat; Report available: 1-2 days
Reference Range
5.0-10.0 mg/L
Clinical Significance
Tobramycin is an aminoglycoside antibiotic used in the treatment of gram-negative bacterial infections, especially Pseudomonas, Proteus, Klebsiella and also Staphylococcus. Tobramycin is potentially nephrotoxic and ototoxic and serial monitoring of peak and trough serum levels may provide the clinician with information to maintain safe and therapeutic levels.
Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153