Thyroid Peroxidase and Thyroglobulin Antibodies

Test Code
7260


CPT Codes
86376, 86800

Preferred Specimen
1 mL serum


Patient Preparation
Dietary supplements containing biotin may interfere in assays and may skew results to be either falsely high or falsely low. For patients receiving the recommended daily doses of biotin, draw samples at least 8 hours following the last biotin supplementation. For patients on mega-doses of biotin supplements, draw samples at least 72 hours following the last biotin supplementation.

Minimum Volume
0.6 mL


Instructions
Administration of STRENSIQ may interfere in certain assays and may falsely elevate values. For patients receiving STRENSIQ, consideration should be given to using alternate methods.


Transport Temperature
Refrigerated (cold packs)


Specimen Stability
Room temperature: 4 days
Refrigerated: 7 days
Frozen: 28 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly lipemic


Methodology
Immunoassay (IA)

Setup Schedule
Set up: Mon-Fri; Report available: 1-4 days


Reference Range
Thyroid Peroxidase Ab <9 IU/mL
Thyroglobulin Ab ≤1 IU/mL


Clinical Significance
Measurement of thyroglobulin antibodies and thyroid peroxidase antibodies is useful in the diagnosis and management of a variety of thyroid disorders including autoimmune thyroiditis, Hashimoto's Disease, Graves Disease and certain types of goiter.


Performing Laboratory
Quest Diagnostics Nichols Institute Chantilly
14225 Newbrook Dr
Chantilly, VA 20153



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.