B-Type Natriuretic Peptide (BNP)

Test Code

37386

CPT Codes
83880

Preferred Specimen

1 mL frozen plasma collected in a plastic EDTA (lavender-top) tube

Minimum Volume

0.5 mL

Instructions

Centrifuge tube and separate plasma into a plastic screw-cap vial within 1 hour. Freeze plasma immediately.
Please note: BNP is unstable in glass containers. Use of glass tubes and glass transfer pipettes will affect accurate quantitation of BNP.

Transport Container

Plastic screw-cap vial

Transport Temperature

Frozen

Specimen Stability

Room temperature: 1 hour
Refrigerated: 1 hour
Frozen: 9 months

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Collected in a glass tube • PPT potassium EDTA (white-top) tube

Methodology
Immunoassay (IA)

Setup Schedule

Set up: Mon-Sat a.m.; Report available: Next day

Reference Range

<100 pg/mL

Clinical Significance

BNP is increased in congestive heart failure, left ventricular hypertrophy, acute myocardial infarction, coronary angioplasty, and hypertension. Elevations are also observed in pulmonary hypertension (indicating right ventricular dysfunction), acute lung injury, hypervolemic states, chronic renal failure and cirrhosis. Decreasing levels indicate therapeutic response to anti-hypertensive therapy.

Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.