Steroid Panel, PCOS/CAH Differentiation

Test Code

90426

CPT Codes
84403, 84402, 82626, 82157, 83498, 82634

Includes

Testosterone, Total, LC/MS/MS
Testosterone, Free
DHEA, Unconjugated
Androstenedione
17-Hydroxyprogesterone
11-Deoxycortisol

Preferred Specimen

1 mL serum collected in a red-top tube (no gel)

Minimum Volume

0.6 mL

Instructions

Collect specimen in red-top tube (no gel); spin down immediately and pour off into a 13x75 plastic transport tube.

Transport Container

Plastic screw-cap vial

Transport Temperature

Frozen

Specimen Stability

Room temperature: 6 hours
Refrigerated: 72 hours
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Serum separator tubes (SST) • Gross hemolysis • Moderate hemolysis • Gross lipemia • Gross icterus • Plasma

Methodology
Chromatography/Mass Spectrometry • Equilibrium Dialysis

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

Set up: Sun, Tues; Report available: 4-9 days

Reference Range

See individual tests

Clinical Significance

This panel is important in the differential diagnosis of PCOS vs. non-classical CAH in women with oligomenorrhea/amenorrhea and signs of androgen excess.

Performing Laboratory

Quest Diagnostics Nichols Institute-San Juan Capistrano, CA

33608 Ortega Highway

San Juan Capistrano, CA 92675-2042

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.