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PAX8, IHC without Interpretation
Test Code90224
CPT Codes
88342
Preferred Specimen
1 formalin fixed paraffin block submitted in IHC Specimen Transport Kit
Minimum Volume
1 block • 3 slides
Other Acceptable Specimens
3 Slides Unstained, positively charged slides IHC Specimen Transport Kit
Instructions
Please include surgical pathology report
Transport Temperature
Room temperature
Specimen Stability
Room Temperature: Indefinitely
Refrigerated: Indefinitely
Frozen: Do Not Freeze
Refrigerated: Indefinitely
Frozen: Do Not Freeze
Methodology
Immunohistochemistry (IHC)
Setup Schedule
Set up: Mon-Fri; Report available: Next day
Reference Range
See Laboratory Report
Clinical Significance
PAX8, a nuclear transcription factor, is expressed, along with PAX2, in renal cell carcinoma, but not in urothelial carcinoma (which is positive for uroplakin III and P63). Other uses include detection of metastatic ovarian serous tumors (as opposed to mesothelioma).
Performing Laboratory
Quest Diagnostics Nichols Institute |
14225 Newbrook Drive |
Chantilly, VA 20153 |