Immunoglobulin M (IgM)

Test Code

545

CPT Codes
82784

Preferred Specimen

1 mL serum

Minimum Volume

0.5 mL

Transport Container

Plastic screw-cap vial

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

Room temperature: 72 hours
Refrigerated: 7 days
Frozen: 90 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Gross hemolysis • Grossly lipemic • Grossly icteric

Methodology
Immunoturbidimetric

Setup Schedule

Set up: Sun-Fri; Report available: 1 day

Reference Range

Cord Blood

6-25 mg/dL

1-28 days

10-50 mg/dL

1-3 months

10-72 mg/dL

4-6 months

12-86 mg/dL

7-11 months

13-120 mg/dL

1 year

23-130 mg/dL

2 years

25-135 mg/dL

3-5 years

26-150 mg/dL

6-8 years

25-150 mg/dL

9-11 years

40-160 mg/dL

12-16 years

41-170 mg/dL

≥17 years

50-300 mg/dL

Clinical Significance

Increased IgM is associated with Waldenström's macroglobulinemia, infectious mononucleosis, viral infections, nephrotic syndrome, and estrogen therapy; decreased IgM is found in selective IgM deficiency, Bruton's Disease, and acquired immune deficiency.

Performing Laboratory

Quest Diagnostics Nichols Institute

14225 Newbrook Drive

Chantilly, VA 20153

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.