Immunoglobulin M (IgM)

Test Code
545


CPT Codes
82784

Preferred Specimen
1 mL serum


Minimum Volume
0.5 mL


Transport Container
Plastic screw-cap vial


Transport Temperature
Refrigerated (cold packs)


Specimen Stability
Room temperature: 72 hours
Refrigerated: 7 days
Frozen: 90 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly lipemic • Grossly icteric


Methodology
Immunoturbidimetric

Setup Schedule
Set up: Sun-Fri; Report available: 1 day


Reference Range
Cord Blood 6-25 mg/dL
1-28 days 10-50 mg/dL
1-3 months 10-72 mg/dL
4-6 months 12-86 mg/dL
7-11 months 13-120 mg/dL
1 year 23-130 mg/dL
2 years 25-135 mg/dL
3-5 years 26-150 mg/dL
6-8 years 25-150 mg/dL
9-11 years 40-160 mg/dL
12-16 years 41-170 mg/dL
≥17 years 50-300 mg/dL


Clinical Significance
Increased IgM is associated with Waldenström's macroglobulinemia, infectious mononucleosis, viral infections, nephrotic syndrome, and estrogen therapy; decreased IgM is found in selective IgM deficiency, Bruton's Disease, and acquired immune deficiency.


Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.